ZHANG Xi1,RUI Rui2,Ll Peipei1,FENG Cuining1,LEl Qiang1,LONG Yue1
Abstract:
By using water as extraction reagent,the polysaccharides in Radix Aconiti Kusnezoffi were extrac-ted.The results showed that optimum extraction condition was 90℃,4 h,and liquid to material ratio 1:50.Four polysaccharide complexes were prepared using four metal ions(Ca2+,Zn3+,Cu2+,Fe3+) and polysaccha-rides from Radix Aconiti Kusnezoffi,respectively. All complexes were evaluated for biological activity againstthree human cancer cell lines (HepG2,MCF-7 and HT-29) by the standard MTT method, and the resultsshowed that PRS-Cu possessed the highest growth inhibitory effects.The complex was characterized by UV,IR,D,SEM, and TGA.