Analysis of Flow Field Characteristics and Hemolysis Evaluation in Oxygenator
[1]LIU Deping,ZHENG Kai,LI Dongmei.Analysis of Flow Field Characteristics and Hemolysis Evaluation in Oxygenator[J].Journal of Zhengzhou University (Engineering Science),2022,43(05):39-45.[doi:10.13705/j.issn.1671-6833.2022.05.006]
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Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
43卷
Number of periods:
2022 05
Page number:
39-45
Column:
Public date:
2022-08-22
- Title:
- Analysis of Flow Field Characteristics and Hemolysis Evaluation in Oxygenator
- Keywords:
- oxygenator; porous media; microscale; computational fluid dynamics; hemolysis
- CLC:
- N945；TH789
- DOI:
- 10.13705/j.issn.1671-6833.2022.05.006
- Abstract:
- Fluid motion in oxygenator has an important influence on its performance, but it is difficult to observe its internal hemodynamics directly. In order to understand the fluid movement characteristics in an oxygenator and predict its performance, this study analyzed the distribution of blood velocity, pressure and wall shear stress in a typical oxygenator through pressure drop experiment and CFD numerical simulation. The hemolysis performance of the oxygenator was evaluated by the hemolysis prediction model. The research results indicated that in the low flow range, the simulated value of the isotropic porous media model was the same as the experimental value，and the model could well simulate the flow of blood in the oxygenator fiber bundle，but with the increase of flow，the deviation increases gradually; the internal velocity of the compound oxygenator was in a gradient form; the internal pressure was concentric and uniform, and the pressure value was positively correlated with the flow rate. The porous medium area was the main area of pressure loss，accounting for 87% of the overall pressure drop; the high incidence of blood damage was located at the blood inlet and outlet. Under the experimental flow, the standard hemolysis index NIH was 0.049 2 g/100 L, which conformed to the general design requirements of oxygenator. The results were helpful for researchers to understand the influence of fluid motion characteristics on the performance of oxygenator, and could provide a reference for further performance improvement of oxygenator.
- References:
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2022-08-20