Optimization of Micro-channel Structure for Microfluidic Droplet Detection Chip Based on Joint Evaluation
[1]DONG Xinmin,ZHANG Hongli,XU Gang,et al.Optimization of Micro-channel Structure for Microfluidic Droplet Detection Chip Based on Joint Evaluation[J].Journal of Zhengzhou University (Engineering Science),2022,43(04):47-52.[doi:10.13705/j.issn.1671-6833.2021.06.006]
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Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
43卷
Number of periods:
2022 04
Page number:
47-52
Column:
Public date:
2022-07-03
- Title:
- Optimization of Micro-channel Structure for Microfluidic Droplet Detection Chip Based on Joint Evaluation
- Keywords:
- droplet detection chip; channel structure; combination weighting; rank-sum ratio method; joint evaluation
- CLC:
- O35
- DOI:
- 10.13705/j.issn.1671-6833.2021.06.006
- Abstract:
- In order to explore the droplet detection chip with short detection instrument time,small continuous phase reagent consumption and small single column spacing,the micro-channel simulation geometric model was established,and the model validity verification experiment was carried out.Using Fluent simulation software,and simulating 16 kinds of droplet detection chips with different structural sizes in the orthogonal experiment,the subjective weighting method and the objective weighting method were combined to form a combination weighting method to weight the evaluation indicators.TOPSIS and RSR were used to jointly evaluate the numerical simulation results,and the order of superiority and inferiority of 16 kinds of structures were obtained.The evaluation results showed that a droplet detection chip with the optimal size structure could be obtained in the conditions of the continuous phase channel size of 80 μm,the discrete phase channel size of 90 μm,the cross exit channel size of 100 μm and the channel depth of 50 μm.The droplet detection chip with that structure consumed less continuous phase reagent per unit time and could produce the performance with smaller droplet sequence spacing and short detection interval time of single droplet.
- References:
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Last Update:
2022-07-03