Optimization of Micro-channel Structure of Flow Focusing Microfluidic Chip

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Optimization of Micro-channel Structure of Flow Focusing Microfluidic Chip

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[1]XU Gang,LIANG Shuai,LIU Wufa,et al.Optimization of Micro-channel Structure of Flow Focusing Microfluidic Chip[J].Journal of Zhengzhou University (Engineering Science),2020,41(04):87-91.[doi:10.13705/j.issn.1671-6833.2020.04.003]

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Journal of Zhengzhou University (Engineering Science)[ISSN 1671-6833/CN 41-1339/T] Volume: 41卷 Number of periods: 2020 04 Page number: 87-91 Column: Public date: 2020-08-12

Title:: Optimization of Micro-channel Structure of Flow Focusing Microfluidic Chip

Author(s):: XU Gang1; 2; LIANG Shuai2; LIU Wufa1; ZHENG Peng1; 1.School of Mechanical and Power Engineering,Zhengzhou University,Zhengzhou 450001,China;2.Guangdong Shunde Innovation Design Institute,Foshan 528311,China

Keywords:: microfluidic chip; channel structure; orthogonal design method; TOPSIS

CLC:: -

DOI:: 10.13705/j.issn.1671-6833.2020.04.003

Abstract:: This study aimed to explore a microfluidic chip that could generate a single droplet with a short cycle,consume a small amount of continuous phase reagents,and have low processing costs.The FLUENT simulation and VOF method were employed to simulate 16 microfluidic chips with different structure sizes in orthogonal experiments.Finally,the TOPSIS was used to comprehensively evaluate the numerical simulation results,and the order of superiority and inferiority of 16 structures was obtained.The evaluation results showed that a microfluidic chip with the optimal size structure could be obtained under the conditons of the continuous phase channel size was 40 μm,the discrete phase channel size was 30 μm,the cross exit channel size was 25 μm and the channel depth was 20 μm.The microfluidic chip could be produced the performance with smaller droplets,highest frequency and consumes less continuous phase reagent per unit time.

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Last Update: 2020-10-06