Scientific prediction of regional highway traffic is the premise and basis of regional highway network planning. After analyzing the changes of highway traffic in China since 1980, it is pointed out that in the future, cars should be used as the standard for measuring highway traffic, on this basis, the four-stage predictive analysis theory is used to research and establish a highway traffic forecasting model and method suitable for the characteristics of Henan Province, and the demand generation, traffic distribution, transportation mode selection and traffic distribution of highway traffic in Henan Province are predicted and analyzed. The actual data of the traffic volume of Luohe-Zhumadian Expressway in 2007 are verified, and the results show that the prediction model established by using the four-stage analysis and prediction theory can better predict the highway traffic volume in Henan Province.