Preparation of novel GC stationary phases and their splitting studies of chiral compounds

Cellulose tris(3,5-dimethylphenylcarbamate) was synthesized and used as a stationary phase by gas chromatography to prepare chiral capillary columns to investigate its polarity, column efficiency and chiral selectivity. The results showed that the stationary phase was moderately polar, with a theoretical plate count of 1 895 m-1 and a capacity factor of 1.52.The column successfully isolated 25 of the 20 randomly selected racemic compounds (including alcohols, ethers, amines, esters, aldehydes, ketones, amino acids), including (±)-Dihydrocarvylacetate, (±)-Roseoxide, (±)-N-Benzyl-1-phenylethylamine, (±)- Fenchone, DL-Leucine and DL-Isoleucine had good separation effects, which confirmed that the column had good chiral separation performance and could be used in gas chromatography.