two-phase anaerobic system;  acetylspiramycin wastewater;  Anaerobic baffle reactor (ABR);  Memorrhizic anaerobic composite bed reactor (UBF).

The productive application of two-phase anaerobic system in the treatment of antibiotic wastewater showed that when the influent pH, VFA, COD and BOD5 of the two-phase anaerobic system were 5.46, 1376 mg/L, 8597 mg/L, 4126 mg/L, respectively, and the residence time of the acid generator (anaerobic baffle reactor) was 12 h, the pH increased from 5.46 to 6.18, the VFA increased from 1376 mg/L to 3281 mg/L, and the BOD5/COD increased from 0 .48 to 0. 52; When the residence time of the methanogenerator (anaerobic composite bed reactor) was 39 h, the removal rates of COD and BOD5 were 90, respectively. 4% and 94.5%.