Polyethylene glycol phase transfer catalyzed synthesis of p-nitroanisole process
[1]Zhang Yadong,Gao Xiaolei,Jiang Denggao,et al.Polyethylene glycol phase transfer catalyzed synthesis of p-nitroanisole process[J].Journal of Zhengzhou University (Engineering Science),2002,23(02):23-26.[doi:10.3969/j.issn.1671-6833.2002.02.007]
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Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
23
Number of periods:
2002年02期
Page number:
23-26
Column:
Public date:
1900-01-01
- Title:
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Polyethylene glycol phase transfer catalyzed synthesis of p-nitroanisole process
- CLC:
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- Abstract:
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The synthesis of p-nitroanisole from p-nitrochlorobenzene from p-nitrochlorobenzene with different molecular weights polyethylene glycol (PEG) as a phase transfer catalyst was studied, the effects of polyethylene glycol molecular weight and the number of polyoxyethylene (-OCH2CH2-) unit links (also known as average polymerization) in the molecular structure on the reaction rate were investigated, the effects of sodium hydroxide, catalyst concentration and dosage on the reaction were investigated, and the catalytic reaction mechanism of PEG phase transfer was elaborated. A suitable process condition for the synthesis of p-nitroanisole under the catalytic condition of PEG phase transfer was established, that is, the temperature was 78~80 °C, n(PCNB)∶n(CH3OH)∶n(NaOH)∶n(P EG-400)=1∶3∶3∶(0.025~0.05), and the reaction time was about 7~8 h
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Last Update:
1900-01-01
