[1]ZHANG Xi,RUI Rui,Ll Peipei,et al.Preparation,Characterization, and Anticancer Evaluation of Inner MongoliaRadix Aconiti Kusenezoffi Polysaccharide Metal Complexes[J].Journal of Zhengzhou University (Engineering Science),2016,37(03):36-.[doi:10.13705/ j.issn.1671 -6833.2016.03.008]
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Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
37
Number of periods:
2016 03
Page number:
36-
Column:
Public date:
2016-05-10
- Title:
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Preparation,Characterization, and Anticancer Evaluation of Inner MongoliaRadix Aconiti Kusenezoffi Polysaccharide Metal Complexes
- Author(s):
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ZHANG Xi1; RUI Rui2; Ll Peipei1; FENG Cuining1; LEl Qiang1; LONG Yue1
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1.College of Chemistry and Molecular Engineering , Zhengzhou University , Zhengzhou 450001 , China; 2. Department of Endo-scope,Xilinguole Meng Mongolian General Hospital,Xilinhaote 026000 , China
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- Keywords:
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radix aconiti kusnezoffii; polysaccharide metal complex; preparation; characterization; antican-cer activity
- CLC:
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O629.1
- DOI:
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10.13705/ j.issn.1671 -6833.2016.03.008
- Abstract:
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By using water as extraction reagent,the polysaccharides in Radix Aconiti Kusnezoffi were extrac-ted.The results showed that optimum extraction condition was 90℃,4 h,and liquid to material ratio 1:50.Four polysaccharide complexes were prepared using four metal ions(Ca2+,Zn3+,Cu2+,Fe3+) and polysaccha-rides from Radix Aconiti Kusnezoffi,respectively. All complexes were evaluated for biological activity againstthree human cancer cell lines (HepG2,MCF-7 and HT-29) by the standard MTT method, and the resultsshowed that PRS-Cu possessed the highest growth inhibitory effects.The complex was characterized by UV,IR,D,SEM, and TGA.