Simultaneous Determination of Quinolinic Acid and Quinoline with High Performance Liquid Chromatography
[1]ZHAO Jian-hong,Ll Ya-fang,WANG Jian-she,et al.Simultaneous Determination of Quinolinic Acid and Quinoline with High Performance Liquid Chromatography[J].Journal of Zhengzhou University (Engineering Science),2013,34(04):73-76.[doi:10.3969/j.issn.1671-6833.2013.04.017]
Copy
Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
34
Number of periods:
2013 04
Page number:
73-76
Column:
Public date:
2013-09-09
- Title:
- Simultaneous Determination of Quinolinic Acid and Quinoline with High Performance Liquid Chromatography
- Keywords:
- high performance liquid chromatography ; electrochemical synthesis; quinolinic acid; quinoline
- CLC:
- O657.7
- Abstract:
- A method was presented for the simultaneous determination of quinolinic acid and quinoline in theelectrochemical synthesis reaction liquid by high performance liquid chromatography ( HPLC). The analysiswas performed on a Hypersil C18 column with a mixture of V( methanol ):V( phosphate buffer solution with0.1% tetrabutyl ammonium hydroxide ,pH =7.0) = 50:50 as the mobile phase at a flow rate of 0.9 mL ·min’. The samples were detected at 254 nm with an UV detector and the column temperature was 30 ℃. Itwas found that quinolinic acid and quinoline could be well separated under the chromatographic conditions.The linear range of the mass concentration were 0.09 ~0.89 g·L ’ and 0.10 g·L-’ ~0.92 g ·L respec-tively. The recoveries for them were 98.4% ~ 102.0% and 98.80% ~ 99.70%. The maximum relativestandard deviations were 0.70% and 0.56% for quinolinic acid and quinoline.
- References:
- -
- Similar References:
Memo
-
Last Update:
1900-01-01