A Solvent-free Method for ERL-4221 by Epoxidation of 3-Cyclohexenylmethyl3’-CyclOhexenecarboxylate with Hydrogen Peroxide
[1]ZHANG Yadong,CHU Jinchang,WANG Zhenxing,et al.A Solvent-free Method for ERL-4221 by Epoxidation of 3-Cyclohexenylmethyl3’-CyclOhexenecarboxylate with Hydrogen Peroxide[J].Journal of Zhengzhou University (Engineering Science),2009,30(04):58-61.
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Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
30
Number of periods:
2009年04期
Page number:
58-61
Column:
Public date:
1900-01-01
- Title:
- A Solvent-free Method for ERL-4221 by Epoxidation of 3-Cyclohexenylmethyl3’-CyclOhexenecarboxylate with Hydrogen Peroxide
- Keywords:
- solvent—free method; epoxidation; 3-Cyclohexenylmethyl一3 7-Cyclohexenecarboxylate; 3; 4-Epoxycyclohexylmethyl一3’; 4’-Epoxycyclohexane Carboxylate
- CLC:
- -
- DOI:
- -
- Abstract:
- Chloromethylated polystyrene divinylbenzene grafted quaternary ammonium salt of phosphor—tungsticheteropoly acid had been prepared as acatalyst．The catalyst had been characterized by IR spectrum and inductively coupled plasma atomic emission spectrometry． 3，4-Epoxycyclohexylmethyl一3’，4’一EpoxycyclohexaneCarboxylate(A00)had been synthesized by epoxidation of 3一Cyelohexenylmethyl 3 7-Cyclohexeneearboxylate(A)with hydrogen peroxide(W(H202)=34．5％)as oxidant under organic solvent—free condition．The maininfluence factors in the reaction，such as mole ration of A to H2 02，reaction time，temperature，amounts ofcatalyst and SO on，had been studied．The appropriate reaction condition are as fallows(based on 60 mmolA)：reaction temperature 65℃，reaction time 100 minutes，catalyst 5．0 g，n(A)：n(H202)=1：3．Underthe condition．average conversion of A is more than 99％and average yield of AOO is 78．9％．The averagerecovery of catalyst is over 93％．
- References:
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Last Update:
1900-01-01