[1]Ren Baozeng,Li Weiran,LI Chen,et al.Indefinite dilution activity coefficient of four quinolones in water[J].Journal of Zhengzhou University (Engineering Science),2002,23(03):6-9,18.[doi:10.3969/j.issn.1671-6833.2002.03.002]
Copy
Journal of Zhengzhou University (Engineering Science)[ISSN
1671-6833/CN
41-1339/T] Volume:
23卷
Number of periods:
2002年03期
Page number:
6-9,18
Column:
Public date:
1900-01-01
- Title:
-
Indefinite dilution activity coefficient of four quinolones in water
- Author(s):
-
Ren Baozeng; Li Weiran; LI Chen; etc
-
-
- Keywords:
-
- CLC:
-
-
- DOI:
-
10.3969/j.issn.1671-6833.2002.03.002
- Abstract:
-
According to the solid-liquid phase equilibrium theory, combined with the characteristics of reversed-phase liquid chromatography process, a model for the determination of infinite dilution activity coefficient in water by liquid chromatography direct method was established. According to this model, the activity coefficient of unlimited dilution of four quinolones such as ofloxacin in water at different temperatures was measured by ion suppression chromatography, which not only provided key basic data for the evaluation of the environmental behavior of quinolones, but also provided a basis for exploring the biological activity mechanism and predicted efficacy of quinolones.