Biopolysaccharides are fermented products with viscosities up to 10 Pa*s, which are highly viscosity non-Newtonian fluids. Its decolorization is achieved by mixing with the decolorizing agent, and the common decolorization process is mechanical stirring intermittent production, which consumes a lot of energy and does not have good effect. The use of static mixer can realize the continuous treatment of biological polysaccharides and decolorizing agents, with short mixing time, low energy consumption and good effect. In the process of decolorization, pH value, amount of decolorizing agent and mixing time all affect the effect of decolorization. The corresponding change curve and the regression formula of pressure loss were obtained, and the optimal operating conditions were found.