Combined with the actual needs of the networked manufacturing system in the Cheng, German and Mianshan regions, the requirements for the e-mail system were analyzed. Furthermore, a hierarchical and distributed e-mail system architecture is proposed, and its network structure and software architecture are elaborated and studied. The network structure is divided into Internet layer, load balancing layer and internal network layer; Its software architecture is divided into: presentation layer, business logic layer and message processing layer. And in the Redhat Linux 9 environment, its detailed configuration process is given. It plays a consolidating role in the stable operation of the networked manufacturing system, and has certain reference and guiding significance for the construction of large-scale mail system.