[1]刘德平,郑 凯,李冬梅.基于氧合器内部流场特性分析与溶血评估[J].郑州大学学报(工学版),2022,43(05):39-45.
 Analysis of Flow Field Characteristics and Hemolysis Evaluation in Oxygenator[J].Journal of Zhengzhou University (Engineering Science),2022,43(05):39-45.
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基于氧合器内部流场特性分析与溶血评估()
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《郑州大学学报(工学版)》[ISSN:1671-6833/CN:41-1339/T]

卷:
43
期数:
2022年05期
页码:
39-45
栏目:
出版日期:
2022-08-22

文章信息/Info

Title:
Analysis of Flow Field Characteristics and Hemolysis Evaluation in Oxygenator
作者:
刘德平1 郑 凯1 李冬梅2
文献标志码:
A
摘要:
氧合器内部流体运动特性对其性能有着重要影响,实际中却难以通过实验直接观察其内部血液流动特性。 为了解氧合器内部流体运动特性以预测其性能,针对一款典型氧合器,采用压降实验与CFD 数值模拟相结合的方法,详细分析了该氧合器内部整体血液速度、压力和壁面剪切应力等特性分布规律,利用溶血预估模型评估了氧合器溶血性能。 研究结果表明:在低流量范围内,各向同性多孔介质模型能够很好地模拟血液在氧合器纤维束内的流动,数值模拟计算值与实验值相差较小,但随着流量增加,两者偏差逐渐增大;氧合器内部速度呈梯度分布形式,内部纤维束域的压力呈同心均匀分布并且压力值与流量大小呈正相关,纤维束域是压力损失的主要区域;血液损伤高发位置分布于血液的进、出口流域,在实验流量范围内,标准溶血指数 NIH 最大值为 0. 049 2 g / 100 L,符合氧合器的一般设计要求。研究结果有利于开发者了解氧合器内部流体运动特性对其性能的影响,为氧合器后续的性能改善提供参考。
Abstract:
Fluid motion in oxygenator has an important influence on its performance, but it is difficult toobserve its internal hemodynamics directly. In order to understand the fluid movement characteristics in an oxygenator and predict its performance,this study analyzed the distribution of blood velocity ,pressure andwall shear stress in a typical oxygenator through pressure drop experiment and CFD numerical simulation. Thehemolysis performance of the oxygenaltor was evalualed by the hemolysis prediction model. The research resultsindicated that in the low flow range ,the simulaled value of the isotropic porous media model was the same asthe experimental value , and the model could well simulalte the flow of blood in the oxygenator fiber bundle , butwith the increase of flow , the deviation increases gradually; the internal velocity of the compound oxygenatorwas in a gradient form; the internal pressure was concentric and uniform, and the pressure value was positivelycorrelaled with the flow rale. The porous medium area was the main area of pressure loss , accounting for 87%of the overall pressure drop; the high incidence of blood damage was located at the blood inlel and outlel.Under the experimental flow , the standard hemolysis index NIH was 0.049 2 g/100 L, which conformed to thegeneral design requirements of oxygenator. The results were helpful for researchers to understand the influenceof fluid motion characleristics on the performance of oxygenator,and could provide a reference for further per-formance improvement of oxygenator.
更新日期/Last Update: 2022-08-20