[1]潘成学,魏俊杰,王彩芳,等.角柱花石油醚部位化学成分研究[J].郑州大学学报(工学版),2012,33(03):103-105.[doi:10.3969/j.issn.1671-6833.2012.03.026]
　PAN Chengxue,WEI Junjie,WANG Caifang,et al.Study on the Chemical Constituents From Petroleum Ether-soluble Portionof Ceratostigma Plumbaginoides Bunge[J].Journal of Zhengzhou University (Engineering Science),2012,33(03):103-105.[doi:10.3969/j.issn.1671-6833.2012.03.026]
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角柱花石油醚部位化学成分研究()
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《郑州大学学报(工学版)》[ISSN:1671-6833/CN:41-1339/T]

卷:
33
期数:
2012年03期
页码:
103-105
栏目:
出版日期:
2012-05-10

文章信息/Info

Title:
Study on the Chemical Constituents From Petroleum Ether-soluble Portionof Ceratostigma Plumbaginoides Bunge
作者:
潘成学; 魏俊杰; 王彩芳; 等.
郑州大学 药学院,河南郑州,450001, 郑州人民医院 药剂科,河南郑州,450003
Author(s):
PAN Chengxue; WEI Junjie; WANG Caifang; etc;
1.School of Pharmaceutical Seiences,Zhengzhou [niversity,Zhengzhou 450001, China; 2. Department of Pharmacy , People’ s Hospital of Zhengzhou.2hengzhou 450003,China
关键词:
角柱花;  白花丹科;  分离;  结构鉴定
Keywords:
ceratostigma plumbaginoides bunge ; ceratostigma ; isolation; structure identification
分类号:
TQ461R931.6
DOI:
10.3969/j.issn.1671-6833.2012.03.026
摘要:
在对角柱花生药学特征进行研究的基础上,对其全草95％乙醇提取物的石油醚部位进行色谱分离,从中分离得到5种化合物,利用MS,1H-NMR,13C-NMR,DEPT及2D-NMR( HMBC,HSQC)谱等现代渡谱技术,确定了它们的结构,分别为为蓝雪醌(Ⅰ),邻苯二甲酸二异丁酯(Ⅱ),香草乙酮(Ⅲ),β-谷甾醇(Ⅳ),6,22-dien-3-hydroxy-5,8 -epidioxy-(3β,5α,8β,22E,24R)-stigmasta(V).以上化合物除蓝雪醌外均为首次从角柱花中分离得到.该研究为建立角柱花的药材品质评价标准,为临床用药安全和新药开发提供实验数据.
Abstract:
Based on the study of pharmacognostic characteristics of ceratostigma plumbaginoides bunge, theherb’ s constituents from the petroleum ether - soluble portion in the 95 9 ethanol extract were isolated andpurified respectively by means of chromatography. Five compounds were isolated. And these compounds wereidentifed by modern spectroscopie technology, such as MS, ’H-NMR, "’C-NMR, DEPT and 2D.NMR( HM.BC, HSQC) ete.. They were respectively elucidated as plumbagin ( I ), dis( 2-methylpropyl) ester( l ) ,Acetovanilone( Ⅲ ),β-sitosterol( I),6, 22-dien-3-hydroxy-5,8-epidioxy-(3β, 5a, 8β, 22E,24R)-stig-masta( Y ). Compounds above were isolated for the first time from ceratostigma plumbaginoides bunge exceptplumbagin, The systemalical study provide experimental data for the quality evaluation, clinical use safety andnew medicine development of this specie8.
更新日期/Last Update: 1900-01-01